R. Lawrence Reed II, MD, FACS, FCCM

Professor of Surgery
Trauma Services Director, Methodist Hospital

Specialty: General Surgery
Residency: William Beaumont Army Medical Center El Paso, Texas
Fellowship: Harborview Medical Center University of Washington (NIH Fellow in Trauma and Burn Research)


Dr. Larry Reed, a board-certified surgeon and specialist in surgical critical care, is Professor of Surgery at Indiana University and Director of Trauma Services at Indiana University Health Methodist Hospital in Indianapolis, IN.  Dr. Reed received his medical degree from the University of Virginia School of Medicine in Charlottesville and completed an internship and residency in General Surgery at William Beaumont Army Medical Center in El Paso, Texas.  He was named a postdoctoral research fellow in respiratory physiology at the Virginia Mason Research Center in Seattle and completed a fellowship in trauma and burn research (through the auspices of the National Institutes of Health) at Harborview Medical Center of the University of Washington, also in Seattle.  His professional responsibilities have included: Associate Chief of the Trauma Service and Surgical Intensive Care Unit at Hermann Hospital (Houston, TX); Chief of General Surgery at the LBJ General Hospital (Houston, TX); Director of the Surgical Intensive Care Unit and Director of the Trauma Center, Duke University University Medical Center; Chief of the Division of Trauma, Surgical Critical Care, and Burns at Loyola University Medical Center; Director of the Surgical Intensive Care Unit at the Edward Hines, Jr. VA Hospital; and the Director of Quality Improvement for the Department of Surgery at Loyola University Medical Center.  He was awarded the Best Teaching Resident at William Beaumont Army Medical Center, the Dean’s Teaching Excellence Award twice at the University of Texas Medical School at Houston, the Davison Award for Excellence in Teaching while at Duke, and at Loyola, he was named the Attending Surgeon of the Year 4 times by the surgical residents.

            A Fellow of both the American College of Surgeons and the College of Critical Care Medicine, Dr. Reed is a member of over 20 professional organizations, including the Society of University Surgeons, The American Association for the Surgery of Trauma, and the Surgical Infection Society.  He is a Past President of the Western Trauma Association.  He has been invited as a Visiting Professor to over 30 healthcare institutions, including the King Faisal Specialist Hospital and Research Centre in Riyadh, Saudi Arabia, and the Middlesex Hospital in London, England.  He has served as a member of the Consultant Committee for Surgical Critical Care for the American Board of Surgery.   He has also served as a member of the Area Committee on Alternative Site Testing for the National Committee for Clinical Laboratory Standards.  He has authored or coauthored more than 75 peer-reviewed articles and 30 book chapters, mostly dealing with critical care, surgical infections, and trauma.  Dr. Reed has long been interested in surgical infections, especially the pharmacokinetic alterations that occur in critically ill and injured patients and how such changes impact the effectiveness of antibiotics.  Among his many other major interests are the use of computerized databases for routine clinical care and quality improvement, resuscitation physiology and monitoring, the influence of hypothermia on blood coagulation, and effective coding and documentation for professional billing purposes.


IU Health Physicians


IU Health Methodist/IU Health University

Location Information

IU Health Methodist Professional Center

1801 N. Senate Blvd., Ste 635

Indianapolis, IN 46202

Clinical Interests


Accepting New Patients

Schedule an Appointment  Clinical Trials

Clinical Research Interests: Surgical infections; antibiotic pharmacokinetics in critically ill and injured patients; hemodynamic and organ function monitoring; computer applications in clinical care; health care financing; quality improvement


  1. Reed, R.L., Maier, R.V., Landicho, D., Kenny, M.A., Carrico, C.J.: Correlation of hemodynamic variables with transcutaneous PO2 measurements in critically ill adult patients. J. Trauma 25(11):1045-1053, 1985.
  2. Reed, R.L., Ciavarella, D., Heimbach, D.M., Baron, L., Pavlin, E., Counts, R.B., Carrico, C.J.: Prophylactic platelets in massive transfusion: a prospective randomized double-blind clinical study. Ann. Surg. 203(1):40-48, 1986.
  3. Reed, R.L., Landicho, D., Kenny, M.A., Gregory, B., Maier, R.V., Carrico, C.J.: Influence of cutaneous perfusion alterations on real-time measurements of PtcO2 and PtcCO2. In: Maas, A.H.J., Boink, A.B.T.J., Saris, N.E.L., Sprokholt, H.R., Wimberley, P.D. (Eds.): Physiology and methodology of blood gases and pH, Proceedings of the 11th International Federation of Clinical Chemistry Expert Panel on pH and Blood Gases and 4th European Working Group on Ion Selective Electrodes 6:55-65, 1986.
  4. Beal, S., Reed, R.L., Heimbach, D.M., Chi, E., Reynolds, L.: Pulmonary microembolism: a cause of lung injury. J. Surg. Res. 43:303-310, 1987.
  5. Reed, R.L., Fischer, R.P.: The management of head injuries. Pulmonary and Critical Care Update 2(19):1-8, 1987.
  6. Kurrek, M.M., Reed, R.L.: Effect of hypothermia on enzymatic activity of thrombin and plasmin. Surg. Forum XXXVIII:221-223, 1987.
  7. Ciavarella, D., Reed, R.L., Counts, R.B., Baron, L., Pavlin, E., Heimbach, D.M., Carrico, C.J.: Clotting factor levels and the risk of microvascular bleeding in the massively transfused patient. Br. J. Haematol. 67:365-368, 1987.
  8. Victor, B.E., Schmidt, K.L., Reed, R.L., Smith, G.S., Thompson, D.A., Miller, T.A.: Gastric injury induced by water immersion stress: prevention by prostaglandin and the role of glutathione. Current Surgery 45(1):20-22, 1988.
  9. Fischer, R.P., Miller-Crotchett, P., Reed, R.L.: Gastrointestinal disruption: the hazard of nonoperative management in adults with blunt abdominal injury. J. Trauma 28(10):1445-1449, 1988.
  10. Johnston, T.D., Reed, R.L.: A hemodynamic monitoring system with intelligence and interventional capabilities. Proc Annu Symp Comput Appl Med Care 12:301-304, 1988.
  11. Gentilello, L.M., Duggan, P., Drummond, D., Tonnesen, A., Degner, E.E., Fischer, R.P., Reed, R.L.: Major injury is a unique opportunity to initiate treatment in the alcoholic. Am. J. Surg. 156(6):558-561, 1988.
  12. Victor, B.E., Schmidt, K.L., Smith, G.S., Reed, R.L., Thompson, D.A., Miller, T.A.: Prostaglandin-induced gastric mucosal protection against stress injury: absence of a relationship to tissue glutathione levels. Ann. Surg. 209(3):289-296, 1989.
  13. Souba, W. W., Roughneen, P. T., Goldwater, D. L., Reed, R.L., Rowlands, B. J.: Effects of enterectomy on postoperative visceral organ glucose exchange. JPEN J Parenter Enteral Nutr 13:128-31, 1989.
  14. Lagerstrom, C.F., Reed, R.L., Rowlands, B.J., Fischer, R.P.: Early fasciotomy for clinically evident post-traumatic compartment syndrome. Am. J. Surg. 158(1):36-39, 1989.
  15. Johnston, T.D., Chen, Y., Reed, R.L.: Relative sensitivity of the clotting cascade to hypothermia. Surg. Forum XL:199-201, 1989.
  16. Reed, R.L., Wu, A.H., Miller-Crotchett, P., Crotchett, J., Fischer, R.P.: Pharmacokinetic monitoring of nephrotoxic antibiotics in surgical intensive care patients. J. Trauma 29(11):1462- 1470, 1989.
  17. Ericsson, C.D., Fischer, R.P., Rowlands, B.J., Hunt, C., Miller-Crotchett, P., Reed, R.L.: Prophylactic antibiotics in trauma: the hazards of underdosing. J. Trauma 29(10):1356-1361, 1989.
  18. Fischer, R.P., Pepe, P.E., Reed, R.L., Parks, D.H., Prentice, F.D., Mattox, K.L.: Academic consequences of a trauma system failure. J. Trauma 30(7):784-791, 1990.
  19. Reed, R.L., Bracey, A.W., Hudson, J.D., Miller, T.A., Fischer, R.P.: Hypothermia and blood coagulation: dissociation between enzyme activity and clotting factor levels. Circ. Shock 32:141-152, 1990.
  20. Reed, R.L.: Antibiotic choices in SICU patients. In: Weigelt, J.A. (ed): Surgical critical care. Surg. Clin. N. Am. Philadelphia: WB Saunders Co., 1991. 71(4):765-789.
  21. Reed, R.L., Johnston, T.D., Chen, Y., Fischer, R.P.: Hypertonic saline alters plasma clotting times and platelet aggregation. J. Trauma 31(1):8-14, 1991.
  22. Reed, R.L., Ericsson, C.D. Wu, A., Miller-Crotchett, P., Fischer, R.P.: The pharmacokinetics of prophylactic antibiotics in trauma. J. Trauma 32(1):21-27, 1992.
  23. Cocanour, C.S., Miller-Crotchett, P., Reed, R.L., Johnson, P.C., Fischer, R.P.: Mucormycosis in trauma patients. J. Trauma 32(1):12-15, 1992.
  24. Reed, R.L., Johnston, T.D., Hudson, J.D., Fischer, R.P.: The disparity between hypothermic coagulopathy and clotting studies. J Trauma 33(3):465-470, 1992.
  25. Reed, R.L. Merrell, R.C., Meyers, W.C., Fischer, R.P.: Continuing evolution in the approach to severe liver trauma. Ann Surg 216(5):524-538, 1992.
  26. Reed, R.L.: Oxygen consumption and delivery. Curr Opin Anaesth 6(2):329-334, 1993.
  27. LaRocco, M.T., Rodriguez, L.F., Chen, C.Y., Smith, G.S., Russell, D.H., Cocanour, C.S., Reed, R.L., Miller, T.A.: Reevaluation of the linkage between acute hemorrhagic shock and bacterial translocation. Circ. Shock 40:212-220, 1993.
  28. Reed, R.L.: Traumatic retroperitoneal hematomas. Curr Surg 50:3:182-188, 1993.
  29. Grewal, R., Reed, R.L.: Accurate charge capture and cost allocation: cost justification for bedside computing. Proc Annu Symp Comput Appl Med Care 17:112-116, 1993.
  30. Johnston, T.D., Fischer, R.P., Chen, Y., Reed, R.L.: Lung injury from gut ischemia: insensitivity to portal blood flow diversion. J. Trauma 35(4):508-511, 1993.
  31. Sladen, R.N., Reed, R.L.: Usefulness of creatinine clearance. Anesth Analg 79(2):398-9, 1994.
  32. Reed, R.L., Sladen, R.N.: An algorithm for hypoxia management. Trauma Quart. 11(1):4-17, 1994.
  33. Reed, R.L.: Monitoring of circulatory oxygen delivery. Trauma Quart. 11(1):18-30, 1994.
  34. Johnston, T.D., Chen, Y., Reed, R.L.: Functional equivalence of hypothermia to specific clotting factor deficiencies. J. Trauma 37(3):413-417, 1994.
  35. Lubarsky, D.A., Smith, L.R., Sladen, R.N., Mault, J.R., Reed, R.L.: Defining the relationship of oxygen delivery and consumption: use of biologic system models. J Surg Res 58(5):503-508, 1995.
  36. Nayduch, D.A., Sullivan, K., Reed, R.L.: Abdominal compartment syndrome. J. Trauma Nursing. 4(1):5-11, 1997.
  37. Bradley, E.L., Young, P.R., Jr., Chang, M.C., Allen, J.E., Baker, C.C., Meredith, W., Reed, L., and Thomason, M.: Diagnosis and initial management of blunt pancreatic trauma: Guidelines from a multiinstitutional review. Ann Surg 1998; 227(6):861-869.
  38. Eachempati, S.R., Sebastian, M.W., Reed, R.L.: Post-traumatic bilateral carotid artery dissection in a patient with fibromuscular dysplasia: a case report and review of the literature. J Trauma 1998; 44(2):406-409.
  39. Eachempati, S.R., Reed, R.L., St. Louis, J..E., Fischer, R.P.: "The demographics of trauma in 1995" revisited: an assessment of the accuracy and utility of trauma predictions. J Trauma 1998; 45(2):208-214.
  40. Reed, R.L. Eachempati, S.R., Russell, M.K., Ziolek, C: Endoscopic placement of jejunal feeding catheters in critically ill patients by a “push” technique. J. Trauma 1998; 45(2):388-393.
  41. Eachempati, S.R., Vaslef, S.N., Sebastian, M.W., Reed, R.L.: Blunt vascular injuries of the neck: Is early heparinization necessary? J. Trauma 1998; 45(6):997-1004.
  42. Hughes, G.C., Smith, A., Eachempati, S.R., Vaslef, S., Reed, R.L.: The use of a temporary vena caval interruption device in high-risk trauma patients unable to receive standard venous thromboembolism prophylaxis. J Trauma 1999;46(2):246-9.
  43.  Eachempati, S.R., Young, C., Alexander, J., Cirisano, F.D., Rodriguez, G.C., Reed, R.L.: The clinical use of an esophageal Doppler monitor for hemodynamic monitoring in sepsis. J Clin Monit Comput 1999;15(3):223-225.
  44. Eachempati, S.R., Barie, P.S., and Reed, R.L: Survival after transabdominal impalement from a construction injury: A review of the management of impalement injuries. J. Trauma 1999;47(5):864-866.
  45. Davis, K.A., Mansour, M.A., Kang, S.S., Labropoulos, N., Esposito, T.J., Silver, G.M., Reed R.L.: Pseudoaneurysms of the extremity without fracture: treatment with percutaneous ultrasound-guided thrombin injection. J Trauma. 2000 Nov;49(5):818-21.
  46. Gamelli, R.L., Cioffi, W. G., DiPietro, L.A., Reed, R.L.: Symposium on surgery in the geriatric patient. Contemporary Surgery 2001;57(6):279-288.
  47. Kuo, R.L., Makhuli, M.J., Eachempati, S.R., Nayduch, D.A., Reed, R.L.: Factors predicting management and outcome in blunt renal trauma. World J Surg 2002 Apr;26(4):416-9
  48. Goto, M., Samonte, V., Khan, M., Haque, F., Goyal, A., Al-Ghoul, W., Raziuddin, S., Fazal, N., Ravindranath, T., Reed, R.L., Gamelli, R.L., Sayeed, M.M..: Enterococcus faecalis exacerbates burn injury-induced host responses in rats. Shock 2002 Dec;18(6):523-8.
  49. Keech, J., Reed, R.L.: Reliability of mixed venous oxygen saturation as an indicator of the oxygen extraction ratio demonstrated by a large patient dataset. J Trauma 2003; 54(2):236-241
  50. Eachempati, S.R., Reed, R.L., Barie, P.S.: Serum bicarbonate concentration correlates with arterial base deficit in critically ill patients. Surg Infect 2003;4(2):193-197.

Department of Surgery | 545 Barnhill Drive, Emerson Hall 203, Indianapolis, In 46202 | Phone: (317) 274-5771