Michele T. Yip-Schneider, PhD

Associate Research Professor of Surgery

Specialty: General Surgery


Michele Yip-Schneider received her PhD in Biochemistry from the University of California, Davis.  Following post-doctoral training at the University of California, Los Angeles and Indiana University School of Medicine, she joined the Department of Surgery faculty at Indiana University School of Medicine in 2001.  Her training in molecular biology and human disease provides the necessary background and expertise to pursue current translational studies in pancreatic cancer.

My research interests include understanding how dysregulated cellular signaling pathways drive pancreatic tumorigenesis.  Specifically, the pathway regulated by the transcription factor nuclear factor-kappaB (NF-kB) has been demonstrated to play a critical role in the development and progression of pancreatic cancer.  Thus, we have been investigating the NF-kB pathway as a promising target.  For these translational studies, our laboratory employs several pre-clinical animal models (standard flank tumor and patient pancreatic tumor tissue xenografts, carcinogen-induced hamster model, genetically engineered mice) to evaluate the chemopreventative and chemotherapeutic potential of various agents for the treatment of pancreatic cancer.  In addition to identifying novel therapeutics, we are also interested in identifying potential biomarkers that can aid in the differential diagnosis of pancreatic lesions.  The development of such biomarkers will facilitate risk stratification of high risk patients and thereby promote early detection and prevention.


Research Page

MeSH Updated
December 14th
​PubMed MEDLINE indexed citations, NLM Catalog records, and the MeSH database have been updated with 2016 MeSH vocabulary.
NLM Catalog modified
December 14th
​The NLM Catalog Journal display has been retired. The Full display now includes "Broad Subject Terms."
Related Citations renamed
June 3rd
To be clearer, the PubMed "Related citations" feature was renamed to "Similar articles."
Save Search Link Renamed
June 3rd
​To help users easily find the feature to create My NCBI email alerts, the "Save search" link was renamed to "Create alert."
PubMed Mobile Updated
April 7th
​PubMed Mobile has been updated with several new features  including additional filters, sort selections, trending articles, and related searches.
Summary display changes
March 26th
​In order to provide a less-cluttered PubMed results display, the status tag lines, e.g., [PubMed - as supplied by publisher], were removed from the Summary results. Other display formats were not modified.
SciENcv Now Supports the NSF Biographical Sketch Format
January 20th
​SciENcv users may now create profiles in the NSF biographical sketch format.
SciENcv Now Supports the New NIH Biographical Sketch Format
January 20th
​SciENcv users may now create biosketchs in the new NIH format, which will become the mandatory format on May 25, 2015. Existing SciENcv biosketches may be duplicated into the new NIH format saving you time and effort. 
MeSH Updated
December 15th
​PubMed MEDLINE indexed citations, NLM Catalog records, and the MeSH database have been updated with 2015 MeSH vocabulary.
NCBI E-Utilities webinar on YouTube
November 17th
​"An introduction to NCBI's E-Utilities, an NCBI API," is now on YouTube.


Department of Surgery | 545 Barnhill Drive, Emerson Hall 203, Indianapolis, In 46202 | Phone: (317) 274-5771